Thousands Sue Weight Loss Drug Manufacturers With Serious Harm AllegationsBy Anthony Yates Thousands of people have come forward alleging serious harm caused by GLP-1 weight loss drugs. Those products include Ozempic, Wegovy, and Mounjaro. According to a report by USA Today, at least 4,400 people have filed lawsuits since the first was filed in 2023. Those suits are now part of a consolidated federal and state litigation and target two drugmakers: Novo Nordisk, which manufactures Ozempic, and Eli Lilly, which makes Trulicity, Mounjaro, and Zepbound. The companies reportedly said they refute the allegations and will defend the safety of their products. The USA Today report focuses on three troubling cases in the growing lawsuit. 63-year-old Todd Engel was using Ozempic to manage his diabetes. However, he told the outlet that he lost vision in one eye after using the drug for four months. His medication reportedly never came up as a potential cause of his sight loss, and he lost vision in his other eye months later. 72-year-old JoHelen McClain reportedly used Wegovy in November 2023, aiming to shed a few pounds. In March 2024, she heard a noise like a "balloon popping," which she later discovered was the sound of her colon rupturing. USA Today also interviewed Mark Smith. He told the outlet that his wife, 62-year-old Robin Smith, was taking Mounjaro for weight loss. She reportedly visited the hospital twice for vomiting. Her doctor suggested she stop using the drug, but her problems persisted. Days later, doctors diagnosed her with Wernicke's encephalopathy, which the outlet explains is a neurological condition caused by a lack of thiamine or Vitamin B1. It's often linked to malnutrition. The outlet points out that an estimated 12% of Americans use GLP-1 weight-loss drugs and that the plaintiff's account for a small percentage of users. USA Today also cites a 2024 court filing by the two drug companies. They explain that the known risks are reflected in FDA-approved labeling, which the FDA has reviewed more than 40 times. USA Today details a Gallup Study, which claims that the usage of GLP-1 drugs doubled between 2024 and 2025.Chief of Research and Development at the St. Louis Veterans Affairs Health Care System, Ziyad Al-Aly, reportedly stated that no medicine is risk-free. However, he believes the benefits outweigh the risks for most patients. Legal challenges are expected to take several years. ARTICLE SOURCE: https://screenrant.com/thousands-sue-weight-loss-drug-manufacturers/
Vegetarian Diet Linked To High Depression Scores, Suggests Large Meta-Analysis
by Jack Dunhill, Social Media Coordinator and Staff Writer
Vegetarian diets could be linked with higher depression scores, suggests a huge meta-analysis of almost 50,000 people by researchers in Bochum, Germany. The research backs up existing studies that have linked ditching meat to an increased likelihood of depression, but the reason why remains elusive.
Whether vegetarianism actually plays a role in depression is poorly understood. Some studies have pointed the finger at the diet, while others have refuted the findings. To identify a link – if there is one – Sebastian Ocklenburg and Jette Borawski performed a large-scale meta-analysis on published studies that compared the depression scores of non-vegetarians and vegetarians. Their results are published in the Journal of Affective Disorders.
After accounting for duplicates, there were a total of 8,057 vegetarians and 41,832 non-vegetarians included in the analysis. While the sample was large, many of the participants were from similar countries, and so the diversity within the study was relatively low.
The researchers then used a statistical program to scour the studies for mood disorder scores and sufficient data to be considered significant, and 13 studies fit the bill.
Once all the findings were analyzed, the researchers discovered a significant increase in the depression scores of vegetarians compared to non-vegetarians. However, while the data was significant, there was also significant heterogeneity in the studies (how conflicting the results were between each study), indicating there was certainly not a unanimous conclusion.
The authors are clear in their paper that they wish to make no conclusions based on the results – it is still unclear whether the link is causal from the diet, or whether those that experience depression are more likely to choose vegetarianism. In one study included in the analysis, for example, the results indicated that more often than not, people with depressive symptoms started their vegetarian diet after the onset of the disorder, suggesting it is not a causal link. It is suggested that depression may make the person more health-conscious, leading them to vegetarianism, or that depression enhances the feelings of empathy towards animals. This is purely speculation at the current time, however.
With a significant link established, the authors now call for further research to understand its true nature. The first step would be to include more countries into the studies, as there is a clear bias in many of the studies towards a small number of countries. Once these are included, identifying whether the diet underlies the symptoms, or is purely a resulting lifestyle, will be incredibly important.
ARTICLE SOURCE: https://www.iflscience.com/vegetarian-diet-linked-to-high-depression-scores-suggests-large-metaanalysis-60524
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