Thousands Sue Weight Loss Drug Manufacturers With Serious Harm AllegationsBy Anthony Yates Thousands of people have come forward alleging serious harm caused by GLP-1 weight loss drugs. Those products include Ozempic, Wegovy, and Mounjaro. According to a report by USA Today, at least 4,400 people have filed lawsuits since the first was filed in 2023. Those suits are now part of a consolidated federal and state litigation and target two drugmakers: Novo Nordisk, which manufactures Ozempic, and Eli Lilly, which makes Trulicity, Mounjaro, and Zepbound. The companies reportedly said they refute the allegations and will defend the safety of their products. The USA Today report focuses on three troubling cases in the growing lawsuit. 63-year-old Todd Engel was using Ozempic to manage his diabetes. However, he told the outlet that he lost vision in one eye after using the drug for four months. His medication reportedly never came up as a potential cause of his sight loss, and he lost vision in his other eye months later. 72-year-old JoHelen McClain reportedly used Wegovy in November 2023, aiming to shed a few pounds. In March 2024, she heard a noise like a "balloon popping," which she later discovered was the sound of her colon rupturing. USA Today also interviewed Mark Smith. He told the outlet that his wife, 62-year-old Robin Smith, was taking Mounjaro for weight loss. She reportedly visited the hospital twice for vomiting. Her doctor suggested she stop using the drug, but her problems persisted. Days later, doctors diagnosed her with Wernicke's encephalopathy, which the outlet explains is a neurological condition caused by a lack of thiamine or Vitamin B1. It's often linked to malnutrition. The outlet points out that an estimated 12% of Americans use GLP-1 weight-loss drugs and that the plaintiff's account for a small percentage of users. USA Today also cites a 2024 court filing by the two drug companies. They explain that the known risks are reflected in FDA-approved labeling, which the FDA has reviewed more than 40 times. USA Today details a Gallup Study, which claims that the usage of GLP-1 drugs doubled between 2024 and 2025.Chief of Research and Development at the St. Louis Veterans Affairs Health Care System, Ziyad Al-Aly, reportedly stated that no medicine is risk-free. However, he believes the benefits outweigh the risks for most patients. Legal challenges are expected to take several years. ARTICLE SOURCE: https://screenrant.com/thousands-sue-weight-loss-drug-manufacturers/
Recipe
Geoff’s Brisket
12-13 lb brisket preferred
Rub of your choice (I prefer kosher salt and coarse ground pepper)
Apple juice (optional)
Squeeze Butter (optional)
Heavy duty aluminum foil or butcher paper. (I’m really liking the butcher paper better than foil these days)
Good Thermometers
The night before:
Trim fat cap to ¼” as well as remove any heavy white chunk fat on the top and where the point meets the flat. Square off flat end as well so it cooks more evenly. The trimmed fat can be made into tallow.
Apply GENEROUS amounts of rub all over starting on the fat cap side and finishing with the meat side up. If doing kosher salt and black pepper, do the salt FIRST liberally, pat it in and top that with heavy pepper …more than liberally. Pepper on top of salt…..always
Place in fridge wrapped in cling wrap and let sit until ready to be put on smoker. I usually do this the night before and smoke the next AM, but the brisket can be put on immediately after rubbing as well if needed. Your smoke ring will pop a little more if you let it sit overnight.
Day of:
Place on smoker at 250 degrees. I prefer fat down to protect the meat from heat from the bottom and the grate doesn’t mess up your bark on the meat side. Either is ok. I put my temperature probes in the thickest part of the meat at this time. (I have a remote temp sensor for both the meat and smoker temps, I highly recommend them)
Spritz with apple juice every two hours (if you choose to)
Don’t open the smoker a lot because “if you are lookin’ you ain’t cookin’…”
Foil or butcher paper wrap at 160-165 internal temp if bark looks right or at the stall…. whichever comes first. If bark needs a little more time then take it to 170. If using the squeeze butter, put it on the brisket liberally then close up foil and put back on smoker.
Continue to 203 deg …. (total cook time “guideline” is 1.00 - 1.5 hours per pound for completion…but go by internal temp for actual). (if you want to chop the whole thing, I would take it to 205 no matter what.)
Pull off smoker and set in cooler still wrapped covered in a towel or in a cool oven still foiled to rest for 1-2 hours before slicing. One hour minimum so that the briskets moisture that was forced outward in cooking can re- distribute while cooling slowly.
Slice the flat for sliced brisket (AGAINST THE GRAIN OF THE MEAT) and you can either slice (against the grain) or chop the point …. Enjoy!
Some thoughts on probing and done-ness….
Monitoring needs to be in the center of the thickest part of the flat ... I like to angle it in to get more of the probe in the meat without passing through the other side I have had to change the location of the probe as well after my target temp was reached because it wasn't right.. ie the probe says 200 but it's still tough and I find the real center is still at 190-195..
This is what works for me. I am not a pro....Just a backyard hack.
I take it to 200 with the monitoring probe. When you reach that temp, I like to take a handheld insta-read thermo like a Thermopop or Lavatools Insta-read and check other areas of the meat for their temp as well just to see how it is going. While doing that I am probing the brisket for tenderness. The probe or knife even needs to pass through all areas of the meat like a hot knife through butter...and if it doesn't....keep taking that center up another couple of degrees. Check at 202...then 204 if need be. 200 is not a magic catch all number for me. It is just a number for me to start probing. Luckily it usually is done at 200-203 but I have had to take it further like described above.
Personally, I’ve rarely had a brisket done under 200 and I've messed up my share taking them off before. The ones I have pulled at 195 or less due to time constraints are like many experience…..dry and tough. It's done when it's done....not before.” A dry tough brisket is an underdone brisket….not an over-cooked brisket. Underdone does not allow the collagen and connective tissues to properly break down and become moisture and subsequently tender.
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