Thousands Sue Weight Loss Drug Manufacturers With Serious Harm AllegationsBy Anthony Yates Thousands of people have come forward alleging serious harm caused by GLP-1 weight loss drugs. Those products include Ozempic, Wegovy, and Mounjaro. According to a report by USA Today, at least 4,400 people have filed lawsuits since the first was filed in 2023. Those suits are now part of a consolidated federal and state litigation and target two drugmakers: Novo Nordisk, which manufactures Ozempic, and Eli Lilly, which makes Trulicity, Mounjaro, and Zepbound. The companies reportedly said they refute the allegations and will defend the safety of their products. The USA Today report focuses on three troubling cases in the growing lawsuit. 63-year-old Todd Engel was using Ozempic to manage his diabetes. However, he told the outlet that he lost vision in one eye after using the drug for four months. His medication reportedly never came up as a potential cause of his sight loss, and he lost vision in his other eye months later. 72-year-old JoHelen McClain reportedly used Wegovy in November 2023, aiming to shed a few pounds. In March 2024, she heard a noise like a "balloon popping," which she later discovered was the sound of her colon rupturing. USA Today also interviewed Mark Smith. He told the outlet that his wife, 62-year-old Robin Smith, was taking Mounjaro for weight loss. She reportedly visited the hospital twice for vomiting. Her doctor suggested she stop using the drug, but her problems persisted. Days later, doctors diagnosed her with Wernicke's encephalopathy, which the outlet explains is a neurological condition caused by a lack of thiamine or Vitamin B1. It's often linked to malnutrition. The outlet points out that an estimated 12% of Americans use GLP-1 weight-loss drugs and that the plaintiff's account for a small percentage of users. USA Today also cites a 2024 court filing by the two drug companies. They explain that the known risks are reflected in FDA-approved labeling, which the FDA has reviewed more than 40 times. USA Today details a Gallup Study, which claims that the usage of GLP-1 drugs doubled between 2024 and 2025.Chief of Research and Development at the St. Louis Veterans Affairs Health Care System, Ziyad Al-Aly, reportedly stated that no medicine is risk-free. However, he believes the benefits outweigh the risks for most patients. Legal challenges are expected to take several years. ARTICLE SOURCE: https://screenrant.com/thousands-sue-weight-loss-drug-manufacturers/
Eating beef staves off cancer, scientists discover
Story by Isobel Williams
A fatty acid in red meat and dairy helps destroy cancer cells (Picture: Getty/Science Photo Libra)© Provided by Metro
Eating red meat and dairy could help to fight cancer, a new study suggests.
Scientists have discovered that a specific fatty acid found in beef, lamb and dairy products improves the body’s ability to attack and kill tumours.
The study, published in the journal Nature, also shows that patients with higher levels of the fatty acid – known as trans-vaccenic acid (TVA) – in their blood responded better to immunotherapy, suggesting that it could work as a nutritional supplement to complement clinical cancer treatments.
‘There are many studies trying to decipher the link between diet and human health, and it’s very difficult to understand the underlying mechanisms because of the wide variety of foods people eat,’ said co-author Professor Jing Chen, of the University of Chicago.
‘But if we focus on just the nutrients and metabolites derived from food, we begin to see how they influence physiology and pathology.
‘By focusing on nutrients that can activate T cell [immune] responses, we found one that actually enhances anti-tumour immunity by activating an important immune pathway.’
Could steak help cure cancer? (Picture: Getty/iStockphoto)© Provided by Metro
For the study, the team started with a database of around 700 known metabolites, small molecules that come from food, and assembled a ‘blood nutrient’ library.
They then screened the compounds in this new library for their ability to influence anti-tumour immunity.
After the scientists evaluated the top six candidates in both human and mouse cells, they saw that TVA performed the best.
‘After millions of years of evolution, there are only a couple hundred metabolites derived from food that end up circulating in the blood, so that means they could have some importance in our biology,’ said Professor Chen.
‘To see that a single nutrient like TVA has a very targeted mechanism on a targeted immune cell type, with a very profound physiological response at the whole organism level – I find that really amazing and intriguing.’
The team found that feeding mice a diet enriched with TVA significantly reduced the tumour growth potential of melanoma and colon cancer cells, as well as enhancing the body’s ability to infiltrate tumours.
Dairy products also contain a ‘good’ fatty acid that appears to help fight cancer (Picture: Getty)© Provided by Metro
They then analysed blood samples from hospital patients undergoing immunotherapy treatment for lymphoma and discovered that patients with higher levels of TVA tended to respond better to treatment than those with lower levels.
Finally, the study discovered that TVA enhanced the ability of an immunotherapy drug to kill leukaemia cells in patients.
However, the authors do not believe eating excessive red meat is the solution and hope to find similar results in plants.
Professor Chen added: ‘There is a growing body of evidence about the detrimental health effects of consuming too much red meat and dairy, so this study shouldn’t be taken as an excuse to eat more cheeseburgers and pizza.
‘There is early data showing that other fatty acids from plants signal through a similar receptor, so we believe there is a high possibility that nutrients from plants can do the same thing by activating the CREB pathway as well.’
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Article Source: https://www.msn.com/en-us/health/medical/eating-beef-staves-off-cancer-scientists-discover/ar-AA1kmI9g
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